Aslan Erdoğan1, Ahmet Güler1, Mehmet Rasih Sonsöz1, Ufuk Yıldız1, Ayşe İrem Demirtola2, Muhammed Mert Göksu1

1Department of Cardiology, Başakşehir Çam Sakura City Hospital, İstanbul, Türkiye
2Department of Cardiology, Bilkent City Hospital, İstanbul, Türkiye

Keywords: Acute myocardial infarcts; coronary; renal stent; under expanded.

Abstract

Acute ST-elevation myocardial infarction with coronary artery ectasia is rare and difficult to treat. The complication rate is high in percutaneous intervention. At the same time, a standard treatment cannot be performed due to the lack of sufficient studies. In this case, complex complications and a different solution technique are presented. Here, we present our experience with a case of acute inferior myocardial infarction in a 62-year-old man with an ectatic right coronary artery and a 1-year follow-up report.

Introduction

Percutaneous coronary intervention in coronary artery ectasia is challenging and portends a high risk of no-reflow and distal embolization.[1,2] In a recent study, no-reflow occurrence was observed in vessels with infarct-related artery diameter >4.0 mm2 . Therefore, the success of interventions in aneurysmal vessels is low. Herein, we report our experience with acute inferior myocardial infarction and ectatic right coronary artery (RCA) in a patient, who underwent a stent implantation and developed a “no-flow phenomenon.”

Case Report

A 62-year-old man was admitted to our hospital with complaints of chest pain. He was a heavy smoker and had hypertension. Electrocardiography revealed >2 mm ST-segment elevation in leads DII, DIII, and aVF. Right coronary angiography showed an occluded lesion in the proximal segment after the aneurysmal ostium. The lesion was crossed with a floppy guidewire. Predilatation was performed with the 2.0×12 mm and 2.5×15 mm balloons (Invader, Alvimedica, Türkiye), and (Invader, Alvimedica, Türkiye). A distal thrombolysis in myocardial infarction (TIMI)-I flow was obtained. Thrombectomy was performed with a thrombus aspiration catheter because of the high thrombus burden. Subsequently, an intracoronary bolus abciximab dose with 0.25 mg/kg was administered, and the infusion dose was continued at a maintenance dose of 0.1 mg/ kg/min. A bare-metal stent (4.5×37 mm; Emphesos II, Alvimedica, Türkiye) was implanted into the lesion. “No-reflow phenomenon” was observed after the stent implantation. Post-dilatation was planned with a non-compliant (NC) balloon, but it could not be advanced through the ostium of the stent. We administered 50 micrograms of adenosine intracoronary. A distal TIMI-II flow was obtained, and we continued the abciximab infusion (Fig. 1).

After 2 days, the control angiography showed a high thrombus burden in the RCA, and the stent was determined to be undersized and malapposed. Due to the large diameter of the artery, a renal stent implantation was planned. The outside of the stent was passed with the Fielder FC (Asahi Intecc, USA). Starting from the distal, the malapposed stent was crushed with the 2.0×12 mm, 2.5×12 mm, and 3.5×20 mm NC balloons (Mozec, Meril, India). After the malapposed stent was entirely crushed to the wall, three renal stents (5×19 mm, 6×18 mm, 6×4 mm; Herculink, Abbott, USA) were implanted in an overlapping manner (Fig. 2). The patient was transferred to the intensive care unit. After three days, the patient was discharged with no complaints. After a 1-year follow-up, multidetector coronary angiography revealed that the stent was open (Fig. 3).


Discussion

This case highlights the complex challenges associated with percutaneous coronary intervention in patients with acute myocardial infarction and coronary artery ectasia. Recent studies have noted an increased incidence of no-reflow in infarct-related arteries with diameters exceeding 4.0 mm2 . Consequently, interventions in aneurysmal vessels carry a higher risk of no-reflow and distal embolization, often resulting in lower procedural success rates.[1,2] Furthermore, the presence of thrombus can obscure the true diameter of the aneurysm, complicating the selection of an appropriately sized stent.[2] This difficulty in achieving optimal stent placement is linked to a higher likelihood of early stent thrombosis.

n cases where there is a significant mismatch between vessel diameter and the stent, as encountered in our case, achieving proper apposition of the stent struts to the vessel wall can be challenging, even with high-pressure balloon inflation. As a bailout strategy, non-coronary stents of larger diameters may be utilized. Although no prospective randomized trials are available, retrospective case–control studies have provided valuable insights. Pourdjabbar et al.[3] reported that renal stents could be implanted in the left main coronary artery with large diameters in select cases. Similarly, Çamci et al.[4] documented that renal stents could be used effectively in ectatic vessels during acute coronary syndrome, with mid-term outcomes comparable to those of bare-metal stents.

In our case, the coronary stent was undersized and malapposed, and attempts to cross it with a hydrophilic guidewire were unsuccessful. We therefore proceeded to crush the coronary stent against the vessel wall and implanted three bare-metal renal stents, ultimately achieving a distal TIMI-III flow.

Conclusion

In this case, we describe our bail-out strategy in a patient with coronary artery ectasia and the “no-reflow phenomenon.” The crushing of the undersized stent to the wall and renal stent implantation resulted in successful revascularization of the infarct-related artery. In addition, multidetector coronary angiography performed at the end of the 1-year follow-up showed that the long-term outcome of renal stents could be good.

Cite This Article: Erdoğan A, Güler A, Sonsöz MR, Yıldız U, Demirolta Aİ, Göksu MM. The Crushing of the Undersized Stent to the Coronary Vessel Wall and Renal Stent Implantation as the Bail-out Strategy for Revascularization in a Patient with Acute Myocardial Infarction and Coronary Artery Ectasia. Koşuyolu Heart J 2025;28(1):36–38.

Peer Review

Externally peer-reviewed.

Author Contributions

Concept – A.E.; Design – A.İ.D.; Supervision – A.G.; Funding – M.R.S.; Materials – M.M.G.; Data collection and/or processing – M.M.G.; Data analysis and/or interpretation – U.Y.; Literature search – A.E.; Writing – A.E.; Critical review – A.E.

Conflict of Interest

All authors declared no conflict of interest.

Use for AI for Writing Assistance

No AI technologies utilized.

Financial Disclosure

The authors declared that this study received no financial support.

References

  1. Yip HK, Chen MC, Chang HW, Hang CL, Hsieh YK, Fang CY, et al. Angiographic morphologic features of infarct-related arteries and timely reperfusion in acute myocardial infarction: Predictors of slow-flow and no-reflow phenomenon. Chest 2002;122(4):1322–32. https://doi.org/10.1378/chest.122.4.1322.
  2. Kawsara A, Núñez Gil IJ, Alqahtani F, Moreland J, Rihal CS, Alkhouli M. Management of coronary artery aneurysms. JACC Cardiovasc Interv 2018;11(13):1211–23. https://doi.org/10.1016/j.jcin.2018.02.041.
  3. Pourdjabbar A, Hibbert B, Simard T, Ramirez D, Glover C, O'Brien E. RACER renal stents for large diameter left main coronary artery intervention. Int J Cardiol 2012;156(3):e68–70. https://doi.org/10.1016/j. ijcard.2011.08.064.
  4. Çamci S, Ari H, Sünbül A, Ari S, Melek M, Bozat T. Safety and efficacy results of percutaneous renal stent implantation in patients with acute coronary syndrome with ectatic and aneurysmatic coronary arteries. Postgrad Med 2024;136(1):95–102. https://doi.org/10.1080/00325481.2024.2313447.

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